Vertex Pharmaceuticals Incorpor
VRTX Large CapHealthcare · Biotechnology
Updated: Jun 14, 2026, 22:19 UTC
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Valuation Analysis
About the Company
Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment
Vertex Pharmaceuticals Incorpor Stock at a Glance
Vertex Pharmaceuticals Incorpor (VRTX) is currently trading at $444.93 with a market capitalization of $112.9B. The trailing P/E ratio stands at 26.39x, with a forward P/E of 20.72x. The 52-week range spans from $362.50 to $507.92; the current price is 12.4% below the yearly high. Year-over-year revenue growth stands at +7.8%. The net profit margin stands at 35.51%.
💰 Dividend
Vertex Pharmaceuticals Incorpor currently does not pay a dividend. The company typically reinvests its earnings into growth initiatives and product development.
📊 Analyst Rating
29 analysts rate Vertex Pharmaceuticals Incorpor (VRTX) on consensus: Buy. The average price target is $548.69, implying +23.32% from the current price. Analyst price targets range from $330.00 to $641.00.
Vertex Pharmaceuticals Incorpor: The Investment Case in Detail
Vertex Pharmaceuticals Incorpor (VRTX) operates in the Healthcare — specifically Biotechnology — and is headquartered in United States. Below is a structured read of the investment case built directly from the latest fundamentals, valuation multiples, analyst positioning and smart-money flows. Each section translates raw numbers into the investment logic they imply, so you can decide whether the risk/reward fits your portfolio.
The Bull Case
Earnings growth of 61.4% is outpacing revenue, a sign of operational leverage — fixed costs are being absorbed across a larger base. The combination of a 54.39% gross margin and 38.13% operating margin shows the business converts revenue into profit efficiently — a hallmark of competitive moat. Free cash flow is positive and net margins stand at 35.51%, meaning reported earnings translate into real cash that can fund buybacks, dividends or strategic acquisitions.
What to Watch Next
- The forward P/E of 20.72x is meaningfully below the trailing 26.39x — analysts expect earnings to step up; the next earnings release is the test.
- The analyst consensus price target implies 23.32% upside — if the next two quarters confirm the underlying thesis, target hikes typically follow.
Investment Thesis: Strengths & Weaknesses
- Profitable with 35.51% net margin
- High return on equity (24.2% ROE)
- High gross margin of 54.39% — indicates pricing power
- Analyst consensus: Buy
- Solid balance sheet with low debt (D/E 10.26)
- Positive free cash flow
No significant red flags in current metrics.
Technical Snapshot
The price is in a transition zone relative to the moving averages — no clear signal.
Risk Profile
The data points to relatively defensive market behavior.
Trading Data
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