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Sector: Healthcare
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Collegium Pharmaceutical, Inc.

COLL Small Cap

Healthcare · Drug Manufacturers - Specialty & Generic

Updated: Jun 14, 2026, 22:19 UTC

$34.64
+0.87% today
52W: $29.11 – $50.79
52W Low: $29.11 Position: 25.5% 52W High: $50.79

Price Chart

Key Metrics

P/E Ratio
16.82x
Price-to-Earnings
Forward P/E
4.55x
Forward Price/Earnings
P/S Ratio
1.41x
Price-to-Sales
EV/EBITDA
3.84x
Enterprise Value/EBITDA
Div. Yield
Annual dividend yield
Market Cap
$1.1B
Market Capitalization
Revenue Growth
8.9%
YoY Revenue Growth
Profit Margin
9.41%
Net profit margin
ROE
27.41%
Return on Equity
Beta
0.75
Market sensitivity
Short Interest
20.88%
% of float sold short
Avg. Volume
504,649
Average daily volume

Valuation Analysis

Signal
Undervalued
vs. S&P 500 avg P/E (24.7x)
Analyst Consensus
None
6 analysts
Avg. Price Target
$54.33
+56.85% upside
Target Range
$45.00 – $60.00

About the Company

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, engages in the development and commercialization of medicines for pain management. The company's portfolio includes Jornay PM, a central nervous system stimulant prescription medicine that contains methylphenidate HCl for the treatment of attention deficit hyperactivity disorder; Belbuca, a buccal film that contains buprenorphine for severe and persistent pain that requires an extended treatment period; Xtampza ER, an abuse-deterrent, extended-release, oral formulation of oxycodone for the management of pain severe enough to require daily; Nucynta ER and Nucynta IR, which are extended-release and immediate-release oral formulations of tapentadol, indicated for the management of acute, severe, and persistent pain; and Sympr

Sector: Healthcare Industry: Drug Manufacturers - Specialty & Generic Country: United States Employees: 423 Exchange: NMS

Collegium Pharmaceutical, Inc. Stock at a Glance

Collegium Pharmaceutical, Inc. (COLL) is currently trading at $34.64 with a market capitalization of $1.1B. The trailing P/E ratio stands at 16.82x, with a forward P/E of 4.55x. The 52-week range spans from $29.11 to $50.79; the current price is 31.8% below the yearly high. Year-over-year revenue growth stands at +8.9%. The net profit margin stands at 9.41%.

💰 Dividend

Collegium Pharmaceutical, Inc. currently does not pay a dividend. The company typically reinvests its earnings into growth initiatives and product development.

📊 Analyst Rating

6 analysts rate Collegium Pharmaceutical, Inc. (COLL) on consensus: None. The average price target is $54.33, implying +56.85% from the current price. Analyst price targets range from $45.00 to $60.00.

Collegium Pharmaceutical, Inc.: The Investment Case in Detail

Collegium Pharmaceutical, Inc. (COLL) operates in the Healthcare — specifically Drug Manufacturers - Specialty & Generic — and is headquartered in United States. Below is a structured read of the investment case built directly from the latest fundamentals, valuation multiples, analyst positioning and smart-money flows. Each section translates raw numbers into the investment logic they imply, so you can decide whether the risk/reward fits your portfolio.

The Bull Case

With a gross margin near 89.17%, the company sits in the top tier of its industry — these are the kinds of structural margins that protect earnings during downturns. Return on equity of 27.41% places management among the most capital-efficient operators in the public market — every euro of shareholder capital is working hard. Our valuation screen flags the stock as undervalued relative to its fundamentals — multiples are running below where the cash flow profile would normally justify.

The Bear Case

The debt-to-equity ratio of 297.57% is elevated, meaning the company relies heavily on creditors — refinancing terms will become more important than operational performance in the next economic downturn. Short interest sits at 20.88% of float — a meaningful contingent of professionals is positioned for the share to fall, which deserves attention even if their thesis may turn out to be wrong.

Valuation in Context

The EV/EBITDA multiple of 3.84x is below the historical equity-market average — strategic acquirers would find the cash-flow profile attractive at this level.

What to Watch Next

  • The forward P/E of 4.55x is meaningfully below the trailing 16.82x — analysts expect earnings to step up; the next earnings release is the test.
  • The analyst consensus price target implies 56.85% upside — if the next two quarters confirm the underlying thesis, target hikes typically follow.

Investment Thesis: Strengths & Weaknesses

Strengths
  • High return on equity (27.41% ROE)
  • High gross margin of 89.17% — indicates pricing power
  • Currently flagged as undervalued
  • Positive free cash flow
Weaknesses
  • High leverage (D/E 297.57)
  • High short interest (20.88%)

Technical Snapshot

50-Day MA
$34.04
+1.76% vs. price
200-Day MA
$39.40
-12.08% vs. price
Below 52W High
−31.8%
$50.79
Above 52W Low
+19%
$29.11

The price is in a transition zone relative to the moving averages — no clear signal.

Risk Profile

Market Risk (Beta)
0.75 · Defensive
Moves less than the overall market
Short Interest
20.88% · High
% of float sold short
Debt-to-Equity
297.57 · High
Total debt / equity

The data points to relatively defensive market behavior, elevated short interest (20.88%), higher leverage relative to equity.

Trading Data

50-Day MA: $34.04
200-Day MA: $39.40
Volume: 278,459
Avg. Volume: 504,649
Short Ratio: 12.97
P/B Ratio: 3.59x
Debt/Equity: 297.57x
Free Cash Flow: $332.6M

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